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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK2 All Species: 40.61
Human Site: T41 Identified Species: 55.83
UniProt: P24941 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P24941 NP_001789.2 298 33930 T41 K I R L D T E T E G V P S T A
Chimpanzee Pan troglodytes XP_523720 325 36841 M61 K I R L D L E M E G V P S T A
Rhesus Macaque Macaca mulatta XP_001113345 298 33812 T41 K I R L D T E T E G V P S T A
Dog Lupus familis XP_856049 298 33839 T41 K I R L D T E T E G V P S T A
Cat Felis silvestris
Mouse Mus musculus P97377 346 38960 T41 K I R L D T E T E G V P S T A
Rat Rattus norvegicus Q63699 298 33869 T41 K I R L D T E T E G V P S T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P13863 303 34670 E41 K I R L E S E E E G V P S T A
Frog Xenopus laevis P23437 297 33852 T41 K I R L D T E T E G V P S T A
Zebra Danio Brachydanio rerio NP_998571 298 34001 T41 K I R L D T E T E G V P S T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P23573 314 35870 T45 K I R L E G E T E G V P S T A
Honey Bee Apis mellifera XP_393450 299 34033 S41 K I R L E T E S E G V P S T A
Nematode Worm Caenorhab. elegans P34556 332 38277 D59 K I R L E S E D E G V P S T A
Sea Urchin Strong. purpuratus XP_790847 299 34142 S41 K I R L D T E S E G V P S T A
Poplar Tree Populus trichocarpa XP_002306004 294 33768 D41 K I R L E Q E D E G V P S T A
Maize Zea mays P23111 294 33816 D41 K I R L E Q E D E G V P S T A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P24100 294 34012 D41 K I R L E Q E D E G V P S T A
Baker's Yeast Sacchar. cerevisiae P00546 298 34043 D48 K I R L E S E D E G V P S T A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.8 99.6 98.9 N.A. 85.2 98.6 N.A. N.A. 65.3 88.9 90.2 N.A. 62.7 69.9 56.9 75.9
Protein Similarity: 100 79.6 99.6 99.6 N.A. 85.8 99.6 N.A. N.A. 77.8 94.9 94.9 N.A. 74.8 82.2 69.8 88.6
P-Site Identity: 100 86.6 100 100 N.A. 100 100 N.A. N.A. 80 100 100 N.A. 86.6 86.6 80 93.3
P-Site Similarity: 100 86.6 100 100 N.A. 100 100 N.A. N.A. 93.3 100 100 N.A. 93.3 100 93.3 100
Percent
Protein Identity: 66.4 66.7 N.A. 67.1 62.4 N.A.
Protein Similarity: 83.2 82.2 N.A. 81.5 79.1 N.A.
P-Site Identity: 80 80 N.A. 80 80 N.A.
P-Site Similarity: 86.6 86.6 N.A. 86.6 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 53 0 0 30 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 48 0 100 6 100 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 6 0 0 0 100 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 100 0 6 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % P
% Gln: 0 0 0 0 0 18 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 18 0 12 0 0 0 0 100 0 0 % S
% Thr: 0 0 0 0 0 53 0 48 0 0 0 0 0 100 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _